Getting zaptel set up to use an E1 card for MFC/R2
First you need to install the zaptel drivers, as you would for any other use of the Digium cards. Then you need to configure the /etc/zaptel.conf file to put the channels into the appropriate mode. For a TE405P/TE410P running 4 E1s of MFC/R2 you will want something like this:

# MFC/R2 does not normally use CRC4
span=1,1,0,cas,hdb3
span=2,0,0,cas,hdb3
span=3,0,0,cas,hdb3
span=4,0,0,cas,hdb3
#
cas=1-15:1101
cas=17-31:1101
#
cas=32-46:1101
cas=48-62:1101
#
cas=63-77:1101
cas=79-93:1101
#
cas=94-108:1101
cas=110-124:1101