An antidepressant is a medication used primarily in the treatment of depression. pamelor Depression can occur if some of the chemicals called neurotransmitters in the brain are not functioning effectively. asendin There are three specific chemicals that can affect a person's mood zyprexa Antidepressants affect one or more of these chemicals in different ways to help stabilize the chemical imbalance often seen in depression. desyrel zyprexa desyrel