This is the same as 6459, but with a bit more info
System dual AMD 64 FC4 Mono 1.1.9.bin installer

rodney@dyer ~ $ cat /etc/ld.so.conf
include ld.so.conf.d/*.conf
/usr/local/lib
/usr/lib
/usr/lib64
/usr/X11R6/lib64
/usr/X11R6/lib
/usr/lib/mysql
/usr/lib64/mysql
/opt/mono-1.1.9/lib
rodney@dyer ~ $ /sbin/ldconfig -p | grep gnomesharp
        libgnomesharpglue.so (libc6,x86-64) => /usr/local/lib/libgnomesharpglue.so
        libgnomesharpglue.so (libc6,x86-64) => /usr/lib/libgnomesharpglue.so
        libgnomesharpglue.so (libc6) => /opt/mono-1.1.9/lib/libgnomesharpglue.so
        libgnomesharpglue-2.so (libc6,x86-64) => /usr/local/lib/libgnomesharpglue-2.so
        libgnomesharpglue-2.so (libc6,x86-64) => /usr/lib/libgnomesharpglue-2.so
        libgnomesharpglue-2.so (libc6) => /opt/mono-1.1.9/lib/libgnomesharpglue-2.so
rodney@dyer ~ $ export PKG_CONFIG_PATH=/opt/mono-1.1.9/lib/pkgconfig:$PKG_CONFIG_PATH
rodney@dyer ~ $ monodevelop
Unhandled Exception: System.TypeInitializationException: An exception was thrown by the type initializer for Gnome.ModuleInfo ---> System.DllNotFoundException: gnomesharpglue-2
in (wrapper managed-to-native) Gnome.ModuleInfo:gnomesharp_gnome_moduleinfo_get_name_offset ()
in <0x00008> Gnome.ModuleInfo:.cctor ()--- End of inner exception stack trace ---

in <0x00000> <unknown method>
in <0x00025> Gnome.Modules:get_UI ()
in <0x00455> MonoDevelop.SharpDevelopMain:Main (System.String[] args)