From the GUI menu:
radar style - some are better for maps where you jump but may be slower on maps where you don't need that...
scoreboard sort - depends if you're playing a match or for fun, etc
radar/panel opacity/size - I would have these bigger and clearer in a match than when I play for fun
mouse box size - possibly some would change this if they need to be more accurate to jump or have quicker reactions to dodge...