\documentclass[a4paper,12pt]{report}
 
\usepackage{
  rotating,
  multirow
}
  
\begin{document}
 
\begin{table}
\begin{center}
\begin{tabular}{c|c|c|c}
 
%\hline
 \multicolumn{2}{c}{} & \multicolumn{2}{c}{Symmetry} \\
%\hline
\cline{3 - 4}
 \multicolumn{2}{c}{} &  Yes &    No                  \\
%\hline
\cline{3 - 4}
\multirow{2}*{\rotatebox{90}{Split}}
   & Yes &  138 &  2719                  \\
\cline{2 - 4}
   &  No & 5003 & 12290                  \\
%\hline
 
\end{tabular}
\end{center}
\caption[Overview of Assemblies in the MSD]
{
bleah
}
\label{msdOverview}
\end{table}