app.py:

# -*- coding: iso-8859-1 -*-
import sys, os, os.path
import wx
from wx import xrc

class App(wx.App):
    def OnInit(self):
        res = xrc.XmlResource('test.xrc')
        myframe = res.LoadFrame(None, 'frame_1')
        myframe.Show()
        return 1

def main():
    application = App(0)
    application.MainLoop()

if __name__ == '__main__':
    main()

test.xrc

<?xml version="1.0" encoding="ISO-8859-1"?>
<!-- generated by wxGlade 0.5 on Thu May 31 11:49:41 2007 from C:\cygwin\home\100681\rep\trunk\test\automation\test\test.wxg -->

<resource version="2.3.0.1">
    <object class="wxFrame" name="frame_1">
        <style>wxDEFAULT_FRAME_STYLE</style>
        <title>frame_1</title>
    </object>
</resource>