'Add 3 labels, 3 textboxes and 1 commandbutton on form

Private Sub Command1_Click()
    Dim pid As Long, hProcess As Long, hWin As Long
    Dim lpMem As Long, ret As Long, lLenMBI As Long
    Dim lWritten As Long, CalcAddress As Long, lPos As Long
    Dim sBuffer As String
    Dim sSearchString As String, sReplaceString As String
    Dim si As SYSTEM_INFO
    Dim mbi As MEMORY_BASIC_INFORMATION
    sSearchString = Text2
    sReplaceString = Text3 & Chr(0)
    If IsWindowsNT Then 'NT store strings in RAM in UNICODE
       sSearchString = StrConv(sSearchString, vbUnicode)
       sReplaceString = StrConv(sReplaceString, vbUnicode)
    End If
    pid = Shell(Text1) 'launch application (calc.exe in this sample)
    hWin = InstanceToWnd(pid) 'get handle of launched window - only to repaint it after changes
'Open process with required access
    hProcess = OpenProcess(PROCESS_READ_WRITE_QUERY, False, pid)
    lLenMBI = Len(mbi)
'Determine applications memory addresses range
    Call GetSystemInfo(si)
    lpMem = si.lpMinimumApplicationAddress
'Scan memory
    Do While lpMem < si.lpMaximumApplicationAddress
        mbi.RegionSize = 0
        ret = VirtualQueryEx(hProcess, ByVal lpMem, mbi, lLenMBI)
        If ret = lLenMBI Then
            If ((mbi.lType = MEM_PRIVATE) And (mbi.State = MEM_COMMIT)) Then ' this block is In use by this process
                If mbi.RegionSize > 0 Then
                   sBuffer = String(mbi.RegionSize, 0)
'Read region into string
                   ReadProcessMemory hProcess, ByVal mbi.BaseAddress, ByVal sBuffer, mbi.RegionSize, lWritten
'Check if region contain search string
                   lPos = InStr(1, sBuffer, sSearchString, vbTextCompare)
                   If lPos Then
                      CalcAddress = mbi.BaseAddress + lPos
                      Me.Show
                      ret = MsgBox("Search string was found at address " & CalcAddress & "." & vbCrLf & "Do you want to replace it?", vbInformation + vbYesNo, "VB-O-Matic")
                      If ret = vbYes Then
'Replace string in virtual memory
                         Call WriteProcessMemory(hProcess, ByVal CalcAddress - 1, ByVal sReplaceString, Len(sReplaceString), lWritten)
'Redraw window
                         InvalidateRect hWin, 0, 1
                      End If
                      Exit Do
                   End If
                End If
            End If
'Increase base address for next searching cicle. Last address may overhead max Long value (Windows use 2GB memory, which is near max long value), so add Error checking
            On Error GoTo Finished
            lpMem = mbi.BaseAddress + mbi.RegionSize
            On Error GoTo 0
        Else
            Exit Do
        End If
    Loop
Finished:
   CloseHandle hProcess
End Sub

Private Sub Form_Load()
   Caption = "VB-O-Matic"
   Label1 = "Start application:"
   Label2 = "String to find:"
   Label3 = "Replace with:"
   Text1 = "Calc.exe"
   Text2 = "Backspace"
   Text3 = "VB-O-Matic"
   Command1.Caption = "&Launch It!"
End Sub

Private Function InstanceToWnd(ByVal target_pid As Long) As Long
  Dim test_hwnd As Long
  Dim test_pid As Long
  Dim test_thread_id As Long
  test_hwnd = FindWindow(ByVal 0&, ByVal 0&)
  Do While test_hwnd <> 0
   If GetParent(test_hwnd) = 0 Then
      test_thread_id = GetWindowThreadProcessId(test_hwnd, test_pid)
      If test_pid = target_pid Then
         InstanceToWnd = test_hwnd
         Exit Do
      End If
   End If
   test_hwnd = GetWindow(test_hwnd, GW_HWNDNEXT)
  Loop
End Function

Private Function IsWindowsNT() As Boolean
   Dim verinfo As OSVERSIONINFO
   verinfo.dwOSVersionInfoSize = Len(verinfo)
   If (GetVersionEx(verinfo)) = 0 Then Exit Function
   If verinfo.dwPlatformId = 2 Then IsWindowsNT = True
End Function